Background: Adenovirus infections are typically associated with minor respiratory, gastrointestinal, and conjunctival symptoms, with severe cases being more common in immunocompromised individuals. However, our case report details a rare instance of an immunocompetent patient suffering
from disseminated adenovirus resulting in bacteraemia, acute respiratory distress syndrome and encephalitis.

Case Presentation: A previously healthy 49-year-old male presented with symptoms initially suggestive of heat stroke, but rapidly deteriorated developing respiratory distress and fluctuating consciousness. Extensive diagnostic evaluation eventually revealed disseminated adenovirus,
infections notably in cerebrospinal fluid and blood. Supportive management commenced in the intensive care unit. Cidofovir and intravenous immunoglobulins were administered, and the patient was monitored closely for potential complications.

Conclusion: This case emphasises the importance of not underestimating the potential severity of adenovirus infections in otherwise healthy individuals.